Abstract: Introduction: BMD varies in different countries due to different genetic and environmental factors, It is necessary to determine BMD in normal population of Iran. This study was designed by the Rheumatology Research Center to fulfill this task. It was achieved by a grant from the Deputy Ministry for Research, the Ministry of Health, Treatment and Medical Education. Materials and methods: 280 normal Iranians were selected randomly from staffs of Shariati Hospital ...
Abstract: In order to study a possible relation between mechanical bone pains and the BMD, 1335 patients were analyzed as every consecutive patient. The BMD was measured in a cohort study on 5927 patients referred for various reasons to the Rheumatology Research Center, Osteoporosis Unit. The BMD was measured by Dual Energy X-rays Absorptiometry (DEXA) on the lumbar spine (L1-L4) and the femoral neck. Patients having an inflammatory disease such as ...
Abstract: Menopause is one of the most important accelerating factors of bone loss in women. This study was designed to evaluate the effects of the age of menopause on BMD in Iranian women. The women referred for Bone Densitometry who were menopaused and did not have hysterectomy before their menopause were selected as every consecutive patient. Those who had any other risk factor for osteoporosis were excluded. The patients were divided ...
Abstract: In Rheumatoid Arthritis (RA) osteoporosis is secondary. Its cause and its treatment are still controversial. All agents used in post menopausal osteoporosis have been tried for RA osteoporosis. Our work is a prospective open study to demonstrate the efficacy of low dose NF (20 mg daily) in these patients. Sixty two patients with RA and osteoporosis (t score less than 2.5 standard deviation, as defined by WHO) entered the study. BMD ...
Abstract: Natrium Fluoride (NF) is one of the best treatments of osteoporosis because it is cheap, it has no major side effects, and it is effective (Heany et al., Farley et al., Dure-Smith et al., Kanis et al., and Pak et al.). Our work is a prospective open study to demonstrate the efficacy of low dose NF (20 mg daily) in post menopausal osteoporosis. Fifty six patients with osteoporosis (t score less ...
Abstract: Systemic Lupus Erythematosus is not rare in Iran. We have seen 220 cases in children in a population of 893 SLE in the past 16 years. In this study we show the features of SLE in children. The female to male ratio was 86/14. Fever was present in 72% of the patients, weight loss in 40%, malar rash in 72.5%, photosensitivity in 54%, mucosal lesion in 48%, discoid rash in ...
Abstract: In a study on 391 cases of BD presented to the EULAR Congress in 1987 we demonstrated that the following symptoms were seen more frequently in patients with positive pathergy phenomenon: oral aphthosis as the initial manifestation of the disease, genital ulcerations, pseudofolliculitis, and arthralgia. The following symptoms, on the contrary were seen less frequently: oral aphthosis, ankylosing spondylitis. It was interesting to look after those findings, 6 years later, in ...
Abstract: There are 5 major sets of diagnosis criteria for BD: Mason & Barnes, O'Duffy, Dilsen, Japan revised criteria, and the International criteria (the latest one). To evaluate their accuracy we analysed their sensitivity and specificity in 2069 BD and 1519 control patients. The accuracy was calculated by the sum of BD patients fulfilling the criteria and the control patients correctly classified as non BD, divided by the sum of the ...
Abstract: The diagnosis method by Classification And Regression Tree (CART) is gaining more importance every year, specially in Rheumatology by the efforts of the American College of Rheumatology. The classification tree not only provides an accurate tool for diagnosis, it gives a better insight of the manifestations of the disease and the value of different criteria for the diagnosis. In this study we analyzed 1992 Behcet's patients (BP) and 1506 control ...
Abstract: Behcet's disease (BD) is not rare in children, and it's clinical picture differs from that in adults. We studied 66 patients in whom the disease was diagnosed under the age 16 from a population of 2068 BD patients. Comparison of the results with the adults by the student paired t test showed: although the most frequent initial manifestation of BD in children was oral aphthosis (54.5%), it was less frequent ...